The
Drugs of Tomorrow are
in Humans Today
For many commercially relevant
diseases, a discovery platform predicated on the mining of human
proteins offers significant advantages. SimPep™ , the company's
proprietary protein-protein interaction platform, optimizes clinical
predictability by discovering and emulating active protein-protein
interaction sites involved with the regulation of diseases with
unmet needs.
SimPep™ incorporates a unique and
proprietary set of algorithms developed by the scientific founders
of Serometrix. This discovery platform allows the convergence
of vast amounts of data from public domain genome and proteome
resources. Unlike classical molecular modeling approaches, SimPep™
utilizes proprietary design rules taken from evolutionary biology
queues. These design rules allow for the rapid identification
of an array of potential regulatory targets and ligands, all with
a high probability of biological relevance within a specific parallel
regulatory network. These hits are then further refined, confirmed
in vitro, and optimized using standardized structure based tools.
This approach enables Serometrix
to deliver new and novel compounds for disease management, providing
our development partners dramatically improved starting points
for the clinical development of promising new classes of therapeutics.
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